What is Methyl Salicylate?

What is Methyl Salicylate?

So, What Exactly Is Methyl Salicylate? An in depth In Accordance With Menthol

Methyl salicylate is really a normal ester that executes really much like menthol. It really is commonly removed through vapor distillation of wintergreen leaves.

Based on WebMD, methyl salicylate can be found in numerous ointments that are topical purchased within the counter for small joint aches or pains that are muscular. It could additionally be present in intimate items.

So, what exactly is methyl salicylate and just what does it do? Both methyl and menthol salicylate are referred to as counterirritants, this means they cause cooling and warming feelings on your skin. Counterirritants are mainly Responsible for the true title, and response, known as “icy hot.”

A lot of these items really should not be utilized on youngsters due to poisoning issues, which we’ll speak about later on in this essay.

Wintergreen Oil

You might nevertheless be wondering, what exactly is methyl salicylate? You will usually learn about wintergreen“oil or oil of wintergreen.” According to a summary in the Journal of Alternative Complementary Medicine, methyl salicylate could be thepredominant ingredient within the oil and is particularly the purest form in the Highest concentration you shall find. In accordance with an oil wintergreen podcast through the Royal community of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the exact same supply, “…research has revealed that methyl salicylate is a component of the plant’s toolbox within the battle against pathogens and herbivores.” Methyl salicylate smells extremely strongly of mint. Regardless of this, it must additionally be noted that this substance will not belong within the mint genus of plant types. The burning cool feeling is triggered through the TRPA1 channel. Methyl salicylate additionally activates the warmth channel TRPV1, which will be equivalent channel considered to be activated by chilli peppers like capsaicin. Sometimes, wintergreen oil is employed together with peppermint oil, considering that the two in tandem are thought to attenuate effects that are beneficial. Wintergreen oil is acquired by vapor distillation regarding the warmed, water-macerated leaves. It really is sometimes utilized interchangeably with sweet birch oil for flavoring meals and sweets.

Certain Products Which Utilize Methyl Salicylate

Based on drugs.com and goodguide.com, there are several items that have methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Soreness Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Couples Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Residing Aloe Heat Cream

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Extreme Strength Toothache relief

Young Residing Thieves Dentarome Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research published in the Annals of Pharmacotherapy aimed to analyze the effectiveness of methyl salicylate in platelet inhibition when compared to aspirin. Platelet aggregation is another real method of talking about platelets clumping together into the bloodstream. This will be associated with bloodstream clotting.

This study used a sample that is small of healthier guys when you look at the 30-46 a long time. All participants got 162 mg of aspirin before a washout period and then 5 g of 30% methyl salicylate preparation, both to be utilized on the anterior legs. It had been discovered that “both aspirin and MS produced statistically significant platelet inhibition; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There was clearly no big distinction between the 2. This implies that methyl salicylate works because effortlessly as aspirin for platelet aggregation, at minimum in healthier people.

Toxicity Fables and Issues

Research of the substance on the net will expose a number of situation reports of infant death. a things that are few be noted about these. Such infant fatalities usually included the accidental swallowing of pure oil of wintergreen, the concentration that is highest of methyl salicylate you may get.

This does not imply that overdoses can only just take place with ingestion; the substance could be consumed through your skin then incorporated into one’s system. But, it had been present in “Toxicity urban myths: the risk that is actual of Acrylic Use,” published into the Global Journal of Aromatherapy, that, “if 10?ml of a 2.5% formula of wintergreen oil were to be reproduced all at a time to your skin and completely consumed, the dosage would express the exact same level of salicylate present in one single 325?mg aspirin tablet.”

For this reason oil of wintergreen is recognized as to be fairly low-risk with few negative effects. However, it is suggested that brand brand new moms and dads avoid getting the substance when you look at the home, in the off-chance that a baby might get their or her arms onto it.

Also, it really is well worth noting that methyl salicylate is limited to be used in cosmetic makeup products in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among numerous health great things about hemp seed oil constituents, you could find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is most remarkable as being a health plus. The oil additionally contains 10-15% dietary fiber, 20-25% protein, and 20-30% carbohydrates.

A bioassay posted in “The structure of Hemp Seed Oil and its particular Possibleas a source that is important of” reported from the methyl salicylate content of hemp seed oil. Additionally they reported in the other things contained in hemp seed oil, such as for example cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

In Summary

Therefore let’s review what we’ve learned thus far:

Methyl salicylate is really an ester that is natural may be made naturally or synthetically when you look at the lab but is often extracted via vapor distillation of wintergreen leaves.

Oil of wintergreen could be the strongest, purest concentration of methyl salicylate.

USUALLY DO NOT INGEST oil of wintergreen.

Methyl salicylate can also be present in over-the-counter services and products such as for instance toothache ointments and muscle mass discomfort relievers to alleviate pain and result in a soothing feeling. It’s also often utilized in smaller amounts to taste foods and candies.

Wintergreen oil placed on your skin when you look at the doses that are right represent the exact exact cbd same quantity of salicylate present in a single 325 mg aspirin tablet.

Methyl salicylate works effortlessly against platelet aggregation—about as much as aspirin does.

Methyl salicylate is situated in hemp seed oil in trace quantities.

We hope this provides you insight that is further exactly how complex and versatile the cannabis plant is in its constituents and compounds. See our weblog to find out about cannabinoids, CBD, anxiety, or news subjects about dispensaries. Maybe you have utilized methyl salicylate before without acknowledging what it had been? Write to us down when you look at the feedback below. And please feel free to ask any queries about CBD services and products.

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